AB0737 Capillaroscopic patterns in patients with Systemic Sclerosis- Rheumatoid arthritis (SSc-RA) overlap syndrome.

Background Nailfold capillaroscopy is useful for the diagnosis and follow-up of autoimmune rheumatic diseases. Impaired microcirculation one leading factors in local general pathogenesis SSc. Nail-fold video-capillaroscopy (NFVC) stands as most informative at same time simple method used evaluation capillary circulation. Objectives To identify characteristic specific SSc-RA capillaroscopic features. Methods Both hand II – V fingers 32 pts with were subjected to widefield NFC, evaluated using a binocular 20x magnification Olympus microscope analyzed view skin lesions discriminating diffuse limited SSc forms. Results SSc-specific dilatations loops common found all SSc-RA. 1/3 had signs active scleroderma pattern, such loss or “avascular areas” (37,5%) hemorrhages (28%). The morphological abnormalities varying degrees tortuosity/vascular inhomogeneity present 69% examined nailfolds, branching bushy behavior predominated. Architectural disorientation/disarrangement was seen 37,5% them. Mega-capillaries formation subcutaneous plexus presented infrequently 16%. Ramified/bushy capillaries (p<0.04) significantly more frequent patients lab inflammatory (p<0.03). Conclusion Thus, NFVC revealed “mixed” nature changes, combining features (capillary dilation, avascular areas, hemorrhages) RA (various changes loops). Disclosure Interests None declared